Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937215 | 0.83 | L3MBTL1 (0.41) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25330133 | 0.82 | RORC (0.49) | RORCJAK2JAK1 | |
| SCHEMBL24894335 | 0.82 | RORC (0.49) | RORCJAK2JAK1 | |
| SCHEMBL31049054 | 0.81 | MDM4 (0.42) | KMT2A | |
| SCHEMBL27221947 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP2C19KMT2A | |
| SCHEMBL16472054 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AHTTHTR2C | |
| SCHEMBL14372548 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AHTTHTR2C | |
| SCHEMBL16472423 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AHTTHTR2C | |
| SCHEMBL15218647 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AHTTHTR2C | |
| SCHEMBL30994589 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AHTTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026903-A1 | IMIDAZO PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-02-06 | — | — | WO | disclosed |