Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 10/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 10/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 10/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 9/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16714580 | 1.00 | ADORA2A (0.45) | ADORA2AADORA1CDK2CDK5CDK5R1 | |
| SCHEMBL31380760 | 0.80 | ADORA2A (0.41) | ADORA2AADORA1CDK2CDK5CDK5R1 | |
| SCHEMBL15922243 | 0.80 | SIGMAR1 (0.36) | — | |
| SCHEMBL17314968 | 0.77 | — | — | |
| SCHEMBL15931260 | 0.77 | — | — | |
| SCHEMBL17314967 | 0.77 | — | — | |
| SCHEMBL20097141 | 0.76 | ADORA2A (0.64) | ADORA2AADORA1CDK2CDK5CDK5R1 | |
| SCHEMBL29661424 | 0.76 | CDK1 (0.41) | ADORA2AADORA1CDK1POLBADORA2B | |
| SCHEMBL183091 | 0.76 | CDK1 (0.41) | ADORA2AADORA1CDK1POLBADORA2B | |
| SCHEMBL24476415 | 0.73 | GAA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026903-A1 | IMIDAZO PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-02-06 | — | — | WO | disclosed |