Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29661424 | 1.00 | CDK1 (0.41) | CDK1YTHDC1GDAKDM4EPIK3CD | |
| SCHEMBL11556607 | 0.81 | CDK1 (0.54) | CDK1YTHDC1GDAKDM4EPIK3CD | |
| SCHEMBL12311046 | 0.81 | ADORA2A (0.46) | CDK1GDAKDM4EPIK3CDPOLB | |
| SCHEMBL31625164 | 0.78 | CDK1 (0.37) | CDK1YTHDC1 | |
| SCHEMBL1397023 | 0.78 | CDK1 (0.37) | CDK1YTHDC1 | |
| SCHEMBL24476718 | 0.76 | CDK1 (0.30) | CDK1 | |
| SCHEMBL31380754 | 0.76 | ADORA2A (0.45) | CDK1POLBADORA2AADORA2BADORA1 | |
| SCHEMBL183206 | 0.76 | ADORA2A (0.45) | CDK1YTHDC1ADORA2AADORA2BADORA1 | |
| SCHEMBL24476380 | 0.76 | CSNK2A1 (0.37) | ADORA2AADORA2B | |
| SCHEMBL16714580 | 0.76 | ADORA2A (0.45) | CDK1POLBADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608317-A4 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2006-12-27 | — | — | EP | claimed |
| EP-1608317-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS | Takeda San Diego, Inc. (US) | 2005-12-28 | — | — | EP | claimed |
| US-20050004117-A1 | Dipeptidyl peptidase inhibitors | SYRRX, INC. | 2005-01-06 | — | — | US | claimed |
| WO-2004087053-A9 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX INC (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004087053-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX, INC. (US) | 2004-10-14 | — | — | WO | claimed |
| US-20260092053-A1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2026-04-02 | — | — | US | disclosed |
| EP-4681774-A2 | KHK INHIBITORS | Gilead Sciences, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | KINETA INC (US) | 2025-11-20 | — | — | US | disclosed |
| EP-4313967-B1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2025-11-12 | — | — | EP | disclosed |
| US-20250333424-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2025-10-30 | — | — | US | disclosed |
| EP-3768260-B1 | OXADIAZOLE COMPOUNDS AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | HOFFMANN LA ROCHE (CH) | 2025-10-08 | — | — | EP | disclosed |
| US-12410160-B2 | KHK inhibitors | GILEAD SCIENCES, INC. (US) | 2025-09-09 | — | — | US | disclosed |
| WO-2004087053-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX, INC. (US) | 2004-10-14 | — | — | WO | disclosed |
| US-5583137-A | Heterocyclic compounds for enhancing antitumor activity | PFIZER INC. (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0626964-A1 | HETEROCYCLIC COMPOUNDS FOR ENHANCING ANTITUMOR ACTIVITY | PFIZER INC. (US) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993017021-A1 | HETEROCYCLIC COMPOUNDS FOR ENHANCING ANTITUMOR ACTIVITY | PFIZER, INC. (US) | 1993-09-02 | — | — | WO | disclosed |
| US-4147867-A | ANTITUMOR AGENTS | GOLOVCHINSKAYA ELENA S | 1979-04-03 | — | — | US | disclosed |
| US-4147867-A | ANTITUMOR AGENTS | GOLOVCHINSKAYA ELENA S | 1979-04-03 | — | — | US | disclosed |
| US-4122173-A | POLYETHYLENE COATING | GOLOVCHINSKAYA ELENA SEMENOVNA | 1978-10-24 | — | — | US | disclosed |
| US-4122173-A | POLYETHYLENE COATING | GOLOVCHINSKAYA ELENA SEMENOVNA | 1978-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004117-A1 | Dipeptidyl peptidase inhibitors | DPP9, DPP4, DPP3 | CDK1 728/4885YTHDC1 4385/4885GDA 3219/4885 |
| US-20260092053-A1 | KHK INHIBITORS | KHK, SLC5A2, HK1 | CDK1 2211/4885YTHDC1 3205/4885GDA 4658/4885 |
| US-20250333424-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, IRF3 | CDK1 1098/4885YTHDC1 533/4885GDA 726/4885 |
| US-12410160-B2 | KHK inhibitors | KHK, KHDRBS1, NADK | CDK1 1003/4885YTHDC1 1669/4885GDA 3641/4885 |
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | TDP1, TDP2, PIKFYVE | CDK1 1075/4885YTHDC1 2276/4885GDA 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.