Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.43 |
| ▸ | MAPT | P10636 | 11/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10853904 | 0.98 | MEN1 (0.44) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL8415307 | 0.81 | MEN1 (0.42) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL5509464 | 0.78 | MEN1 (0.40) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL16322074 | 0.78 | MAPT (0.40) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL7646733 | 0.78 | MAPT (0.40) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL9232235 | 0.76 | KMT2A (0.45) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL1426467 | 0.76 | MEN1 (0.39) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL7796649 | 0.75 | MAPT (0.38) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL11181041 | 0.74 | MEN1 (0.37) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL6956406 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025027567-A1 | PROCESS FOR PREPARING MAVACAMTEN AND PROCESS INTERMEDIATE | OLON S.P.A. (IT) | 2025-02-06 | — | — | WO | disclosed |