SCHEMBL1426467

SCHEMBL1426467

CC(C)CC(C)N1C(=O)CC(=O)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 0.39
KMT2A Q03164 10/20 0.39
MAPT P10636 13/20 0.36
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 3/20 0.34
ALDH1A1 P00352 4/20 0.33
PTGS1 P23219 2/20 0.33
TOP2A P11388 2/20 0.33
TOP2B Q02880 2/20 0.33
RAB9A P51151 1/20 0.33
HSD17B10 Q99714 5/20 0.32
TDP1 Q9NUW8 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HBB P68871 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
PKM P14618 1/20 0.31
CYP2C19 P33261 1/20 0.31
PSMD14 O00487 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7646733 0.83 MAPT (0.40) MEN1KMT2AMAPTLMNAL3MBTL1
SCHEMBL16322074 0.83 MAPT (0.40) MEN1KMT2AMAPTLMNAL3MBTL1
SCHEMBL4002598 0.82 BMPR1B (0.32) MEN1KMT2AMAPTL3MBTL1ALDH1A1
SCHEMBL11792257 0.81 MAPT (0.39) MEN1KMT2AMAPTLMNAL3MBTL1
SCHEMBL10535947 0.81 MAPT (0.36) MEN1KMT2AMAPTLMNAALDH1A1
SCHEMBL7796649 0.80 MAPT (0.38) MEN1KMT2AMAPTLMNAL3MBTL1
SCHEMBL10853904 0.78 MEN1 (0.44) MEN1KMT2AMAPTLMNAL3MBTL1
SCHEMBL31380893 0.76 MEN1 (0.43) MEN1KMT2AMAPTLMNAL3MBTL1
SCHEMBL4582755 0.75 ALDH1A1 (0.37) MEN1KMT2AMAPTLMNAL3MBTL1
SCHEMBL8415307 0.75 MEN1 (0.42) MEN1KMT2AMAPTLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9668943-B2 Dental conditioning composition KABUSHIKI KAISHA SHOFU (JP) 2017-06-06 US claimed
US-20260144715-A1 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH SHOFU INC. (JP) 2026-05-28 US disclosed
EP-4717251-A2 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH Shofu Inc. (JP) 2026-04-01 EP disclosed
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2026-03-12 US disclosed
EP-3733152-B1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC (JP) 2026-03-11 EP disclosed
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
EP-4659729-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION Shofu Inc. (JP) 2025-12-10 EP disclosed
US-20250195339-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2025-06-19 US disclosed
US-20250195336-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION FOR LUTING EXCELLENT IN ADHESIVE PROPERTY AND REMOVABILITY OF EXCESS CEMENT SHOFU INC. (JP) 2025-06-19 US disclosed
EP-4541338-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION CONTAINING ORGANIC FILLER Shofu Inc. (JP) 2025-04-23 EP disclosed
US-20060247330-A1 Two paste-type glass ionomer cement KABUSHIKI KAISHA SHOFU (JP) 2006-11-02 US disclosed
EP-1066813-B1 Dental adhesive composition SHOFU KK (JP) 2004-10-06 EP disclosed
EP-1056432-B1 IMPROVED CATALYTIC POLYMERIZATION ACCELERATOR SYSTEMS MYCONE DENTAL SUPPLY COMPANY I (US) 2003-07-09 EP disclosed
US-6583197-B1 Excellent sustained release of fluorine; free radical polymerizable unsaturated monomer having an acid group, acid-reactive fluoroaluminsilicate glass filler, water, solvent KABUSHIKI KAISHA SHOFU (JP) 2003-06-24 US disclosed
EP-0702948-B1 TOOTH SURFACE TREATING AGENT SHOFU KK (JP) 2001-03-07 EP disclosed
EP-1066813-A2 Dental adhesive composition KABUSHIKI KAISHA SHOFU (JP) 2001-01-10 EP disclosed
EP-1056432-A1 IMPROVED CATALYTIC POLYMERIZATION ACCELERATOR SYSTEMS Mycone Dental Supply Company, Inc. (US) 2000-12-06 EP disclosed
WO-1999043288-A1 IMPROVED CATALYTIC POLYMERIZATION ACCELERATOR SYSTEMS MYCONE DENTAL SUPPLY COMPANY, INC. (US) 1999-09-02 WO disclosed
US-5707611-A Tooth surface treating agent KABUSHIKI KAISHA SHOFU (JP) 1998-01-13 US disclosed
EP-0702948-A1 TOOTH SURFACE TREATMENT KABUSHIKI KAISHA SHOFU (JP) 1996-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION GRIN3A, HBG1, ASIC1 MEN1 3431/4885KMT2A 2629/4885MAPT 2952/4885
US-20250195336-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION FOR LUTING EXCELLENT IN ADHESIVE PROPERTY AND REMOVABILITY OF EXCESS CEMENT BRWD1, ITGA8, PLA2G2C MEN1 4718/4885KMT2A 498/4885MAPT 1937/4885
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 MEN1 2022/4885KMT2A 939/4885MAPT 2976/4885
US-20260144715-A1 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH CAD, SMCHD1, ITGA1 MEN1 2175/4885KMT2A 1586/4885MAPT 991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.