SCHEMBL3138248

SCHEMBL3138248

O=[N+]([O-])c1ccc(Cl)cc1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.64
TSHR P16473 3/20 0.64
GPR35 Q9HC97 3/20 0.62
LMNA P02545 2/20 0.50
POLB P06746 2/20 0.50
VCAM1 P19320 1/20 0.50
MAPT P10636 3/20 0.49
MEN1 O00255 1/20 0.49
GAA P10253 1/20 0.49
KMT2A Q03164 1/20 0.49
ALDH1A1 P00352 6/20 0.49
KCNMA1 Q12791 2/20 0.48
CYP3A4 P08684 3/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32668870 1.00 MAPK1 (0.64) MAPK1TSHRGPR35LMNAPOLB
SCHEMBL305611 0.83 MAPK1 (0.62) MAPK1TSHRGPR35LMNAVCAM1
SCHEMBL27329814 0.82 MAPK1 (0.60) MAPK1TSHRGPR35LMNAVCAM1
SCHEMBL1524058 0.80 MAPK1 (0.72) MAPK1TSHRLMNAPOLBVCAM1
SCHEMBL27895855 0.80 CTSB (0.61) MAPK1TSHRGPR35LMNAPOLB
SCHEMBL10948907 0.79 PDE7A (0.66) MAPK1TSHRGPR35LMNAPOLB
SCHEMBL9198198 0.78 GPR35 (0.67) MAPK1TSHRGPR35LMNAPOLB
SCHEMBL68980 0.78 GPR35 (0.67) MAPK1TSHRGPR35LMNAPOLB
SCHEMBL29479746 0.78 GPR35 (0.67) MAPK1TSHRGPR35LMNAPOLB
SCHEMBL29490141 0.78 GPR35 (0.67) MAPK1TSHRGPR35LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912424-B Method for hydrolyzing nitroaniline substances into phenol 浙江大学 2020-08-07 CN claimed
CN-109912424-A The method that nitroaniline substance is hydrolyzed into phenol 浙江大学 2019-06-21 CN claimed
CN-105621587-A Method for degrading chloro-nitroaromatic by using sulfate radicals UNIV ZHEJIANG 2016-06-01 CN claimed
US-7365231-B2 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2008-04-29 US claimed
US-20060241187-A1 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2006-10-26 US claimed
CN-1207269-C 1,3,5-tri(3-hydroxy-4-aminophenoxy)benzene and its hydrochlorides and preparation thereof UNIV SHANGHAI JIAOTONG (CN) 2005-06-22 CN claimed
CN-1203048-C 3,5-bi(3-hydroxy-4-aminophenoxy)benzoic acid and its hydrochlorides and preparation thereof UNIV SHANGHAI COMMUNICATION (CN) 2005-05-25 CN claimed
CN-1472192-A 3,5-bi(3-hydroxy-4-aminophenoxy)benzoic acid and its hydrochlorides and preparation thereof 上海交通大学 2004-02-04 CN claimed
CN-1472191-A 1,3,5-tri(3-hydroxy-4-aminophenoxy)benzene and its hydrochlorides and preparation thereof 上海交通大学 2004-02-04 CN claimed
US-4310711-A Process for preparing 5-chloro-2-nitrophenol HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-12 US claimed
JP-5294900-A None JP disclosed
CN-122080114-A Composition containing long-chain alkane for polypeptide synthesis and preparation method of polypeptide 2026-05-26 CN disclosed
EP-3981762-B1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MAT CO LTD (CN) 2025-10-15 EP disclosed
WO-2025201453-A1 MACROCYCLIC COMPOUNDS AS RAS INHIBITORS BEIGENE (SUZHOU) CO., LTD. (CN) 2025-10-02 WO disclosed
US-RE50527-E1 Covalent inhibitors of KRAS G12C ARAXES PHARMA LLC (US) 2025-08-12 US disclosed
US-3976488-A COUPLER, EXTENDER, DISPERSION MEDIUM MITA INDUSTRIAL COMPANY, LTD. (JA) 1976-08-24 US disclosed
US-3960831-A WET FASTNESS, COLORFASTNESS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed
US-3950171-A THERMOPLASTIC RESIN DIAZONIUM SALT MITA INDUSTRIAL CO. LTD. (JA) 1976-04-13 US disclosed
US-3948661-A Process for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LTD. (JA) 1976-04-06 US disclosed
US-3944422-A Photosensitive material in use for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LIMITED (JA) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241187-A1 Compound with antitumor activity and preparation method therefor WEE1, WEE2, CYP51A1 MAPK1 2625/4885TSHR 3788/4885GPR35 2929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.