SCHEMBL31384348

SCHEMBL31384348

O=Cc1cc(C=O)cc(OCc2cccc(Cl)c2)c1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.56
MAOA P21397 9/20 0.56
RXRA P19793 1/20 0.55
RXRB P28702 1/20 0.55
RXRG P48443 1/20 0.55
NR4A2 P43354 1/20 0.54
GRM5 P41594 1/20 0.50
ALOX5 P09917 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8985654 0.89 MAOB (0.72) MAOBMAOARXRARXRBRXRG
SCHEMBL3423658 0.88 MAOB (0.65) MAOBMAOARXRARXRBRXRG
SCHEMBL30399352 0.88 MAOB (0.65) MAOBMAOARXRARXRBRXRG
SCHEMBL18002417 0.83 MAOB (0.68) MAOBMAOARXRARXRBRXRG
SCHEMBL31384354 0.82 TACR2 (0.55) MAOBMAOANR4A2
SCHEMBL1664699 0.82 MAOA (0.75) MAOBMAOAALOX5
SCHEMBL18002843 0.81 MAOB (0.71) MAOBMAOANR4A2
SCHEMBL18002427 0.81 MAOB (0.62) MAOBMAOARXRARXRBRXRG
SCHEMBL18002879 0.78 MAPT (0.58) MAOBMAOANR4A2
SCHEMBL578947 0.78 MAOB (0.75) MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119330860-A Bis-aminoguanidine derivative and preparation method and application thereof 中国农业科学院兰州畜牧与兽药研究所 2025-01-21 CN disclosed