Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.65 |
| ▸ | RXRA | P19793 | 1/20 | 0.62 |
| ▸ | RXRB | P28702 | 1/20 | 0.62 |
| ▸ | RXRG | P48443 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 4/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423658 | 1.00 | MAOB (0.65) | MAOBRXRARXRBRXRGRAB9A | |
| SCHEMBL8545870 | 0.89 | RAB9A (0.71) | MAOBRAB9AMAOA | |
| SCHEMBL31384348 | 0.88 | MAOB (0.56) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL8985654 | 0.86 | MAOB (0.72) | MAOBRXRARXRBRXRGRAB9A | |
| SCHEMBL4417316 | 0.84 | MAOB (0.65) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL28115794 | 0.84 | MAOB (0.69) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL18002417 | 0.83 | MAOB (0.68) | MAOBRXRARXRBRXRGRAB9A | |
| SCHEMBL27983208 | 0.83 | RAB9A (0.63) | MAOBRAB9AMAOA | |
| SCHEMBL12578102 | 0.81 | RAB9A (0.55) | MAOBRAB9AMAOA | |
| SCHEMBL1164139 | 0.81 | MAOB (0.74) | MAOBRAB9AMAOANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240557-B | Pyrrolidine amide derivatives and use thereof | 广东东阳光药业有限公司 | 2023-05-09 | — | — | CN | disclosed |