Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.54 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385200 | 1.00 | MLYCD (0.59) | MLYCDMAPK14MEN1KMT2APLA2G1B | |
| SCHEMBL31385327 | 0.87 | PTGER4 (0.55) | MAPK14PTGER4TACR1APPLMNA | |
| SCHEMBL31385191 | 0.84 | MAPK14 (0.62) | MAPK14MEN1KMT2ALMNA | |
| SCHEMBL31347370 | 0.83 | MLYCD (0.57) | MLYCDMAPK14MEN1KMT2APLA2G1B | |
| SCHEMBL12629823 | 0.80 | MLYCD (0.58) | MLYCDMAPK14MEN1KMT2APLA2G1B | |
| SCHEMBL5261051 | 0.79 | MLYCD (0.80) | MLYCDMAPK14MEN1KMT2APLA2G1B | |
| SCHEMBL5113671 | 0.79 | APP (0.74) | MEN1KMT2AAPPLMNA | |
| SCHEMBL16628738 | 0.78 | ADORA2A (0.59) | MLYCDMAPK14PTGER4APP | |
| SCHEMBL31385207 | 0.78 | PTGER4 (0.57) | MAPK14CYP1A2GAACYP2D6CYP2C19 | |
| SCHEMBL4925824 | 0.77 | CNR2 (0.63) | MAPK14CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | disclosed |