Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.62 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GLS | O94925 | 2/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385207 | 0.88 | PTGER4 (0.57) | MAPK14PPARGEPHX2PPARDPPARA | |
| SCHEMBL31385201 | 0.84 | MLYCD (0.59) | MAPK14LMNAMEN1KMT2A | |
| SCHEMBL31385200 | 0.84 | MLYCD (0.59) | MAPK14LMNAMEN1KMT2A | |
| SCHEMBL4927001 | 0.78 | MMP13 (0.79) | MAPK14MMP13 | |
| SCHEMBL31385327 | 0.78 | PTGER4 (0.55) | MAPK14PPARGEPHX2PPARALMNA | |
| SCHEMBL31060144 | 0.77 | MAPK14 (1.00) | MAPK14MMP13ROCK2ROCK1PPARG | |
| SCHEMBL27913707 | 0.75 | ROCK2 (0.87) | MAPK14MMP13ROCK2ROCK1AKR1C3 | |
| SCHEMBL27931717 | 0.75 | ROCK2 (0.65) | MAPK14MMP13ROCK2ROCK1PPARG | |
| SCHEMBL29037122 | 0.75 | MAPK14 (0.56) | MAPK14MMP13ROCK2ROCK1ABCB1 | |
| SCHEMBL5334251 | 0.74 | MMP13 (0.81) | MAPK14MMP13ROCK2ROCK1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | disclosed |