Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12571866 | 0.80 | HTT (0.49) | KDM4EALDH1A1GAAABL1ACACB | |
| Hydrochloric Acid SCHEMBL14842973 | 0.79 | MEN1 (0.44) | BACE1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL21865491 | 0.76 | ALDH1A1 (0.52) | RXFP1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL422040 | 0.75 | IKBKB (0.47) | KDM4EALDH1A1GAAPARP1PLAU | |
| SCHEMBL29668334 | 0.75 | IKBKB (0.47) | KDM4EALDH1A1GAAPARP1PLAU | |
| Hydrochloric Acid SCHEMBL14843117 | 0.74 | IKBKB (0.46) | KDM4EALDH1A1GAAPARP1PLAU | |
| SCHEMBL27808756 | 0.74 | IKBKB (0.46) | KDM4EALDH1A1GAAPARP1PLAU | |
| SCHEMBL15775057 | 0.73 | ALPL (0.50) | BACE1RXFP1KMT2ADGAT1PARP1 | |
| SCHEMBL24457821 | 0.73 | PIK3CA (0.53) | BACE1ROCK2ALDH1A1ABL1ACACB | |
| SCHEMBL29699292 | 0.73 | PIK3CA (0.53) | BACE1ROCK2ALDH1A1ABL1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | claimed |
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | disclosed |