Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385731 | 1.00 | TAAR1 (0.45) | TAAR1CHRNB2CHRNA4 | |
| SCHEMBL31386254 | 0.84 | SLC6A2 (0.42) | TAAR1 | |
| SCHEMBL31386209 | 0.84 | SLC6A2 (0.42) | TAAR1 | |
| SCHEMBL15613943 | 0.82 | HPGD (0.50) | — | |
| SCHEMBL31386143 | 0.81 | CA12 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL31385851 | 0.80 | — | — | |
| SCHEMBL27805833 | 0.80 | — | — | |
| SCHEMBL3236943 | 0.80 | NPC1 (0.47) | — | |
| SCHEMBL31385832 | 0.80 | CHRNB2 (0.46) | CHRNB2CHRNA4 | |
| SCHEMBL29318689 | 0.79 | SLC6A3 (0.52) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727591-A1 | SMARCA2 DEGRADERS AND USES THEREOF | Astrazeneca AB (SE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256988-A1 | SMARCA2 DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2024-12-19 | — | — | WO | disclosed |