Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474077 | 0.88 | MEN1 (0.48) | GSK3BMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL28547135 | 0.84 | GSK3B (0.50) | GSK3BMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL69263 | 0.83 | KDM4E (0.62) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2890548 | 0.82 | KDM4E (0.51) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL25190853 | 0.81 | GSK3B (0.47) | GSK3BMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL6243384 | 0.80 | KDM4E (0.50) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1483403 | 0.80 | TSHR (0.55) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL16957205 | 0.80 | KDM4E (0.50) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29606273 | 0.80 | TSHR (0.55) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3116280 | 0.80 | MAPT (0.50) | MAPTALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727591-A1 | SMARCA2 DEGRADERS AND USES THEREOF | Astrazeneca AB (SE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256988-A1 | SMARCA2 DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2024-12-19 | — | — | WO | disclosed |