SCHEMBL4474077

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31386348	0.88	GSK3B (0.47)	LMNASMN1; SMN2MAPTKDM4EALDH1A1
	SCHEMBL11639359	0.85	CYP4F2 (0.65)	KMT2AALDH1A1TSHRGSK3BCYP4F2
	SCHEMBL70470	0.83	ALDH1A1 (0.65)	MEN1LMNAKMT2ASMN1; SMN2MAPT
	SCHEMBL203438	0.83	GSK3B (0.49)	LMNAMAPTKDM4EALDH1A1TSHR
	SCHEMBL6029423	0.83	CA12 (0.57)	MEN1LMNAKMT2ASMN1; SMN2MAPT
	SCHEMBL2054480	0.83	GSK3B (0.49)	LMNASMN1; SMN2MAPTKDM4EALDH1A1
	SCHEMBL30016749	0.83	CA12 (0.57)	MEN1LMNAKMT2ASMN1; SMN2MAPT
	SCHEMBL6402167	0.81	GSK3B (0.51)	MEN1LMNAKMT2ASMN1; SMN2MAPT
	SCHEMBL28547135	0.81	GSK3B (0.50)	LMNAKMT2ASMN1; SMN2MAPTKDM4E
	SCHEMBL18398130	0.80	GSK3B (0.53)	LMNAMAPTKDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.