SCHEMBL31386688

SCHEMBL31386688

CS(=O)(=O)OCCc1cnn(C2CCCCO2)c(=O)c1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 1/20 0.39
▸ RXRB P28702 1/20 0.39
▸ RXRG P48443 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ LMNA P02545 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ CYP4F2 P78329 5/20 0.35
▸ CYP4A11 Q02928 5/20 0.35
▸ ATR Q13535 6/20 0.32
▸ PARG Q86W56 1/20 0.32
▸ KRAS P01116 1/20 0.32
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ ACVRL1 P37023 1/20 0.31
▸ ACVR1 Q04771 1/20 0.31
▸ PDE9A O76083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31104432 0.94 RXRA (0.38) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31103783 0.83 RXRA (0.35) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31103882 0.78 RXRA (0.42) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31104397 0.78 RXRA (0.45) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31104206 0.78 ALDH1A1 (0.44) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31104287 0.75 ALDH1A1 (0.36) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL30922462 0.74 KRAS (0.37) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31104382 0.73 RXRA (0.41) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL15889590 0.73 ALDH1A1 (0.48) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL18485074 0.72 KDM5B (0.38) RXRARXRBRXRGALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250059161-A1 COMPOUNDS AND METHODS FOR MODULATING STAT3 VIVIDION THERAPEUTICS, INC. 2025-02-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250059161-A1 COMPOUNDS AND METHODS FOR MODULATING STAT3 STAT3, JAK2, STAT1 RXRA 839/4885RXRB 718/4885RXRG 600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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