Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 13/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24529304 | 0.81 | SNCA (0.35) | IRAK4LPLLIPGFFAR1CA1 | |
| SCHEMBL25236019 | 0.78 | IRAK4 (0.34) | IRAK4LPLLIPGFFAR1 | |
| SCHEMBL23998384 | 0.75 | ALDH1A1 (0.37) | IRAK4LPLLIPGFFAR1CA1 | |
| SCHEMBL22650435 | 0.73 | LPL (0.42) | IRAK4LPLLIPGFFAR1 | |
| SCHEMBL24387013 | 0.72 | LPL (0.30) | LPLLIPGFFAR1 | |
| SCHEMBL31489565 | 0.69 | LPL (0.33) | IRAK4LPLLIPG | |
| SCHEMBL517499 | 0.69 | LPL (0.52) | LPLLIPGFFAR1ESR2CA1 | |
| SCHEMBL21630705 | 0.68 | LPL (0.35) | IRAK4LPLLIPGFFAR1 | |
| SCHEMBL17492388 | 0.68 | LPL (0.46) | IRAK4LPLLIPGFFAR1ESR2 | |
| SCHEMBL24529390 | 0.67 | NPC1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2024255765-A1 | NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) | 2024-12-19 | — | — | WO | disclosed |