Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25394098 | 1.00 | CCR1 (0.42) | CCR1CCR5CCR8TDO2KDM4E | |
| SCHEMBL22111943 | 0.81 | NPC1 (0.44) | CCR1CCR5CCR8TDO2KDM4E | |
| SCHEMBL25393628 | 0.81 | TDO2 (0.41) | CCR1CCR5CCR8TDO2KDM4E | |
| SCHEMBL31387568 | 0.81 | TDO2 (0.41) | CCR1CCR5CCR8TDO2KDM4E | |
| SCHEMBL25395725 | 0.81 | TDO2 (0.41) | CCR1CCR5CCR8TDO2KDM4E | |
| SCHEMBL31387624 | 0.81 | TDO2 (0.41) | CCR1CCR5CCR8TDO2KDM4E | |
| SCHEMBL13549952 | 0.78 | NPC1 (0.50) | CCR1CCR5CCR8TDO2KDM4E | |
| SCHEMBL30572342 | 0.78 | SMN1; SMN2 (0.49) | CCR1CCR5CCR8TDO2KDM4E | |
| SCHEMBL1016812 | 0.78 | SMN1; SMN2 (0.49) | CCR1CCR5CCR8TDO2KDM4E | |
| SCHEMBL11064947 | 0.76 | IDO1 (0.51) | CCR1CCR5CCR8KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119137101-A | Compounds, compositions, and methods | 尼科治疗有限公司 | 2024-12-13 | — | — | CN | disclosed |