Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31506670 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TBK1SLC6A9 | |
| SCHEMBL25400457 | 0.75 | BCL2A1 (0.45) | ALDH1A1ARCYP11B1CYP11B2 | |
| SCHEMBL30430517 | 0.75 | BCL2A1 (0.45) | ALDH1A1ARCYP11B1CYP11B2 | |
| SCHEMBL31535180 | 0.75 | KCNJ1 (0.34) | TBK1ARKCNJ1KCNH2 | |
| SCHEMBL31506681 | 0.73 | AR (0.33) | ARKCNJ1KCNH2 | |
| SCHEMBL31506682 | 0.73 | AR (0.33) | ARKCNJ1KCNH2 | |
| SCHEMBL31506657 | 0.72 | AR (0.33) | ARKCNJ1KCNH2 | |
| SCHEMBL31388140 | 0.71 | PGR (0.36) | ARKCNJ1KCNH2 | |
| SCHEMBL15819822 | 0.71 | CHRM4 (0.43) | ARKCNJ1KCNH2FFAR4 | |
| SCHEMBL8433491 | 0.69 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490500-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-02-21 | — | — | CN | disclosed |