Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14054493 | 1.00 | KIF11 (0.61) | KIF11TAAR1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL13741967 | 0.84 | CYP17A1 (0.52) | KIF11ALDH1A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL3789413 | 0.83 | TAAR1 (0.54) | KIF11TAAR1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL30758809 | 0.83 | KIF11 (0.59) | KIF11TAAR1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL3790335 | 0.83 | KIF11 (0.59) | KIF11TAAR1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL9478565 | 0.81 | KIF11 (0.57) | KIF11TAAR1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL28441473 | 0.80 | KIF11 (0.55) | KIF11TAAR1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL21200228 | 0.80 | ALDH1A1 (0.54) | KIF11ALDH1A1CYP3A4TDP1CYP17A1 | |
| SCHEMBL30576799 | 0.80 | KIF11 (0.55) | KIF11TAAR1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL8383368 | 0.79 | TAAR1 (0.50) | KIF11TAAR1ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143691-B | Thiadiazole derivative and preparation method and application thereof | 山东大学日照研究院 | 2025-06-24 | — | — | CN | disclosed |
| CN-119143691-A | Thiadiazole derivative and preparation method and application thereof | 山东大学日照研究院 | 2024-12-17 | — | — | CN | disclosed |