Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729450 | 0.76 | SCN9A (0.46) | SMN1; SMN2RECQL | |
| SCHEMBL31389172 | 0.74 | RAD52 (0.51) | TSHRSMN1; SMN2RAD52ALDH1A1RECQL | |
| SCHEMBL26852628 | 0.72 | PGR (0.33) | HDAC2PGRRAD52ALDH1A1RECQL | |
| SCHEMBL11737036 | 0.71 | BACE1 (0.38) | TSHRPGRLMNATP53 | |
| SCHEMBL12536165 | 0.71 | TSHR (0.47) | PDK2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL31389178 | 0.70 | PDK2 (0.38) | PDK2RAD52ALDH1A1NPSR1LMNA | |
| SCHEMBL31389181 | 0.70 | POLB (0.51) | PDK2SMN1; SMN2NOTUMALDH1A1RECQL | |
| SCHEMBL29547846 | 0.68 | — | — | |
| SCHEMBL26891315 | 0.68 | GRIN2D (0.33) | TSHRHDAC2PGRRAD52LMNA | |
| SCHEMBL20489275 | 0.66 | AKR1B1 (0.32) | HDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264032-A | Preparation method of 3-hydroxy-2-indolone compound | 苏州大学 | 2025-01-07 | — | — | CN | disclosed |