Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25890242 | 0.80 | ADORA3 (0.37) | PDK2GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL3519201 | 0.76 | LMNA (0.37) | GAAL3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL31389184 | 0.75 | SCN9A (0.42) | PDK2GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL31389172 | 0.74 | RAD52 (0.51) | GAAKMT2AMEN1ALDH1A1RAD52 | |
| SCHEMBL8687319 | 0.74 | LMNA (0.35) | GAAKMT2AMEN1ALDH1A1KCNH2 | |
| SCHEMBL21993355 | 0.73 | EGLN1 (0.41) | KCNH2 | |
| SCHEMBL12990219 | 0.72 | PDK2 (0.36) | PDK2KCNH2L3MBTL1ADORA3ADORA2A | |
| SCHEMBL31389183 | 0.70 | PDK2 (0.36) | PDK2ALDH1A1RAD52LMNAMAPT | |
| SCHEMBL23558587 | 0.69 | EGLN1 (0.43) | KCNH2 | |
| SCHEMBL2525874 | 0.68 | BACE1 (0.39) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264032-A | Preparation method of 3-hydroxy-2-indolone compound | 苏州大学 | 2025-01-07 | — | — | CN | disclosed |