Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 3/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389710 | 0.86 | POLB (0.36) | POLBMAPTKDM4EALDH1A1GAA | |
| SCHEMBL31389418 | 0.82 | MAPT (0.37) | POLBMAPTKDM4EALDH1A1GAA | |
| SCHEMBL31389683 | 0.82 | MAPT (0.37) | POLBMAPTKDM4EALDH1A1GAA | |
| SCHEMBL31389674 | 0.80 | POLB (0.41) | POLBMAPTGAA | |
| SCHEMBL31389396 | 0.79 | POLB (0.38) | POLBKDM4EALDH1A1GAA | |
| SCHEMBL31389505 | 0.74 | POLB (0.41) | POLBMAPTGAA | |
| SCHEMBL31389983 | 0.72 | POLB (0.41) | POLBMAPTALDH1A1GAA | |
| SCHEMBL31389485 | 0.72 | POLB (0.58) | POLBTP53MAPTALDH1A1 | |
| SCHEMBL31389778 | 0.71 | PTPN2 (0.38) | POLBMAPTALDH1A1GAA | |
| SCHEMBL21498615 | 0.70 | POLB (0.69) | POLBGAAHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |