Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389786 | 0.84 | POLB (0.43) | POLBCYP1A2CYP2D6MAPTGAA | |
| SCHEMBL31389983 | 0.82 | POLB (0.41) | POLBRAB9ACYP1A2CYP2D6ENPP2 | |
| Bicarbonate SCHEMBL31389668 | 0.80 | POLB (0.40) | POLBRAB9ACYP1A2CYP2D6MAPT | |
| SCHEMBL31389505 | 0.80 | POLB (0.41) | POLBRAB9ACYP1A2CYP2D6ENPP2 | |
| SCHEMBL31389445 | 0.80 | POLB (0.44) | POLBMAPTGAA | |
| SCHEMBL31389710 | 0.80 | POLB (0.36) | POLBRAB9ACYP1A2CYP2D6ENPP2 | |
| SCHEMBL31389396 | 0.78 | POLB (0.38) | POLBRAB9ACYP1A2CYP2D6ENPP2 | |
| SCHEMBL31389418 | 0.78 | MAPT (0.37) | POLBRAB9ACYP1A2CYP2D6MAPT | |
| SCHEMBL31389683 | 0.78 | MAPT (0.37) | POLBRAB9ACYP1A2CYP2D6MAPT | |
| SCHEMBL31389778 | 0.76 | PTPN2 (0.38) | POLBRAB9ACYP1A2CYP2D6ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |