Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380228 | 0.92 | KMT2A (0.41) | RIPK1KMT2AGAANPC1RAB9A | |
| SCHEMBL6380305 | 0.91 | NPC1 (0.43) | RIPK1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL20645944 | 0.81 | RIPK1 (0.64) | RIPK1KMT2AGAAMAPT | |
| SCHEMBL6382710 | 0.80 | NPC1 (0.43) | RIPK1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL31389815 | 0.80 | RIPK1 (0.47) | RIPK1KMT2AGAANPC1RAB9A | |
| SCHEMBL31389773 | 0.80 | RIPK1 (0.47) | RIPK1KMT2AGAANPC1RAB9A | |
| SCHEMBL19255481 | 0.80 | RIPK1 (0.72) | RIPK1KMT2AGAAKDM4EMAPT | |
| SCHEMBL19224504 | 0.80 | RIPK1 (0.72) | RIPK1KMT2AGAAKDM4EMAPT | |
| SCHEMBL31389863 | 0.80 | ATM (0.43) | KMT2AGAACYP1A2ATMFAAH | |
| SCHEMBL31389779 | 0.79 | RIPK1 (0.47) | RIPK1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |