Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379779 | 0.89 | RIPK1 (0.41) | RIPK1POLBPLATESR1P2RY14 | |
| SCHEMBL20645944 | 0.83 | RIPK1 (0.64) | RIPK1POLBPLATTSHRGAA | |
| SCHEMBL31389495 | 0.79 | RIPK1 (0.44) | RIPK1KDM4EGAA | |
| SCHEMBL31389630 | 0.76 | RIPK1 (0.39) | RIPK1POLBPLATESR1HCAR2 | |
| SCHEMBL20213598 | 0.75 | RIPK1 (0.74) | RIPK1POLBHCAR2GRM5 | |
| SCHEMBL19207826 | 0.75 | RIPK1 (0.74) | RIPK1POLBHCAR2GRM5 | |
| SCHEMBL4910441 | 0.74 | USP2 (0.43) | RIPK1POLBUSP2ESR1HCAR2 | |
| SCHEMBL6383954 | 0.74 | USP2 (0.43) | RIPK1POLBUSP2ESR1HCAR2 | |
| SCHEMBL31389640 | 0.72 | RIPK1 (0.34) | RIPK1GRM5 | |
| SCHEMBL31511159 | 0.72 | NOS3 (0.33) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |