Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14433681 | 0.77 | MAPT (0.69) | MAPTLMNAGAAHSD17B10POLB | |
| SCHEMBL14942591 | 0.77 | PDK1 (0.48) | MAPTLMNAGAAHSD17B10TSHR | |
| SCHEMBL31389935 | 0.76 | PDK1 (0.47) | MAPTLMNAGAAHSD17B10TSHR | |
| SCHEMBL17621024 | 0.76 | GAA (0.42) | MAPTLMNAGAAHSD17B10POLB | |
| SCHEMBL21333625 | 0.75 | MAPT (0.66) | MAPTLMNAGAAHSD17B10POLB | |
| SCHEMBL30960184 | 0.74 | LMNA (0.53) | MAPTLMNAGAAPOLBMAPK1 | |
| SCHEMBL8203493 | 0.74 | KDM4E (0.71) | MAPTLMNAGAAHSD17B10POLB | |
| SCHEMBL31389785 | 0.74 | MAPT (0.64) | MAPTLMNAGAAHSD17B10POLB | |
| SCHEMBL12922693 | 0.73 | PARP1 (0.53) | MAPTLMNAGAAHSD17B10POLB | |
| SCHEMBL8005977 | 0.73 | PARP1 (0.50) | MAPTLMNAGAAHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |