Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389606 | 0.80 | KMT2A (0.44) | POLBALDH1A1TSHRGAAKMT2A | |
| SCHEMBL4910441 | 0.75 | USP2 (0.43) | POLBRIPK1ESR1HCAR2ALDH1A1 | |
| SCHEMBL6383954 | 0.75 | USP2 (0.43) | POLBRIPK1ESR1HCAR2ALDH1A1 | |
| SCHEMBL31389638 | 0.73 | — | — | |
| SCHEMBL1423651 | 0.70 | HTR2A (0.44) | — | |
| SCHEMBL31389779 | 0.68 | RIPK1 (0.47) | POLBRIPK1ESR1HCAR2TSHR | |
| SCHEMBL27627731 | 0.68 | APOBEC3A (0.32) | POLBHCAR2 | |
| SCHEMBL23779041 | 0.66 | GRM5 (0.39) | POLBMEN1KMT2A | |
| SCHEMBL21033178 | 0.66 | RIPK1 (0.37) | RIPK1ALDH1A1GAARECQLMEN1 | |
| SCHEMBL22887696 | 0.66 | RIPK1 (0.47) | RIPK1ALDH1A1GAARECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |