Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389674 | 0.84 | POLB (0.41) | POLBCYP1A2CYP2D6EPHX2MAPT | |
| SCHEMBL31389594 | 0.78 | POLB (0.44) | POLBCYP1A2CYP2D6EPHX2MAPT | |
| SCHEMBL21498615 | 0.78 | POLB (0.69) | POLBCYP1A2CYP2D6GAA | |
| SCHEMBL20625250 | 0.74 | GAA (0.51) | POLBCYP1A2CYP2D6EPHX2MAPT | |
| SCHEMBL12654126 | 0.73 | POLB (0.48) | POLBCYP1A2CYP2D6MAPTGAA | |
| SCHEMBL12653859 | 0.73 | POLB (0.48) | POLBCYP1A2CYP2D6MAPTGAA | |
| SCHEMBL30685930 | 0.73 | GAA (0.48) | POLBCYP1A2CYP2D6EPHX2MAPT | |
| SCHEMBL29716145 | 0.73 | GAA (0.48) | POLBCYP1A2CYP2D6EPHX2MAPT | |
| SCHEMBL31389983 | 0.73 | POLB (0.41) | POLBCYP1A2CYP2D6MAPTGAA | |
| SCHEMBL2803614 | 0.72 | CYP1A2 (0.49) | POLBCYP1A2CYP2D6MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |