Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632699 | 0.81 | ATM (0.40) | ATM | |
| SCHEMBL10552586 | 0.80 | — | — | |
| SCHEMBL29955898 | 0.80 | — | — | |
| SCHEMBL23486907 | 0.75 | ATM (0.37) | ATMACHEALDH1A1NPC1USP2 | |
| SCHEMBL17157138 | 0.75 | ATM (0.37) | ATMACHEALDH1A1NPC1USP2 | |
| SCHEMBL58521 | 0.75 | ATM (0.37) | ATMACHEALDH1A1NPC1USP2 | |
| SCHEMBL8539711 | 0.73 | ATM (0.44) | ATMACHEALDH1A1NPC1ACE | |
| SCHEMBL8539717 | 0.73 | ATM (0.44) | ATMACHEALDH1A1NPC1ACE | |
| SCHEMBL5114651 | 0.72 | ACE (0.41) | ACE | |
| SCHEMBL24133161 | 0.72 | ACE (0.41) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |