Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 5/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539717 | 1.00 | ATM (0.44) | ATMACEACHEALDH1A1NPC1 | |
| SCHEMBL8300088 | 0.85 | EPHX1 (0.36) | ATMACHEALDH1A1NPC1 | |
| SCHEMBL8300090 | 0.85 | EPHX1 (0.36) | ATMACHEALDH1A1NPC1 | |
| SCHEMBL2016589 | 0.83 | ALDH1A1 (0.35) | ATMACHEALDH1A1NPC1 | |
| SCHEMBL9258703 | 0.82 | RIPK1 (0.44) | ATMACELMNACYP2C19HSD17B10 | |
| SCHEMBL9258699 | 0.82 | RIPK1 (0.44) | ATMACELMNACYP2C19HSD17B10 | |
| SCHEMBL15355368 | 0.82 | ATM (0.50) | ATMACE | |
| SCHEMBL28022268 | 0.82 | ATM (0.50) | ATMACE | |
| SCHEMBL5319493 | 0.82 | ATM (0.50) | ATMACE | |
| SCHEMBL26604816 | 0.82 | ATM (0.50) | ATMACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565396-B1 | 1-[2-(arylsulfonylamino)-1-oxoethyl]piperidine derivatives, their preparation and use in therapy | SYNTHELABO (FR) | 1998-01-07 | — | — | EP | disclosed |
| EP-0565396-A1 | 1-(2-arylsulfonylamino)-1-oxoethyl)-piperidine derivatives, their preparation and use in therapy | SYNTHELABO (FR) | 1993-10-13 | — | — | EP | disclosed |