Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114651 | 1.00 | ACE (0.41) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL4416268 | 1.00 | ACE (0.41) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL14369222 | 1.00 | ACE (0.41) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL2928936 | 0.94 | ALDH1A1 (0.36) | ACE | |
| SCHEMBL2928932 | 0.94 | ALDH1A1 (0.36) | ACE | |
| SCHEMBL2522460 | 0.92 | L3MBTL1 (0.36) | ACE | |
| SCHEMBL29955898 | 0.86 | — | — | |
| SCHEMBL10552586 | 0.86 | — | — | |
| SCHEMBL2926280 | 0.81 | CA12 (0.38) | — | |
| SCHEMBL3507032 | 0.80 | ACE (0.40) | ACERENLMNACYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260098021-A1 | Nitrosation Reagents and Methods | UNIV CALIFORNIA (US) | 2026-04-09 | — | — | US | disclosed |
| US-12459909-B2 | Nitrosation reagents and methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-04 | — | — | US | disclosed |
| US-20230242495-A1 | Nitrosation Reagents and Methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| US-20230242495-A1 | Nitrosation Reagents and Methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| US-20230242495-A1 | Nitrosation Reagents and Methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| WO-2021257849-A1 | NITROSATION REAGENTS AND METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459909-B2 | Nitrosation reagents and methods | NOS2, NOS1, NNMT | ACE 2226/4885REN 449/4885LMNA 791/4885 |
| US-20260098021-A1 | Nitrosation Reagents and Methods | TXN, CBR1, CBR3 | ACE 2133/4885REN 479/4885LMNA 194/4885 |
| US-20230242495-A1 | Nitrosation Reagents and Methods | NOS2, NOS1, NNMT | ACE 2226/4885REN 449/4885LMNA 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.