Bromide

Bromide

SCHEMBL313908

CCCCCCCCCCCCCCCCCCCCCC[n+]1ccc(C=Cc2ccc(N(C)C)cc2)cc1.[Br-]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHKA known ✓ P35790 2/20 0.62
CHRM2 known ✓ P08172 2/20 0.55
CHRM4 known ✓ P08173 2/20 0.55
CHRM5 known ✓ P08912 2/20 0.55
CHRM1 known ✓ P11229 2/20 0.55
CHRM3 known ✓ P20309 2/20 0.55
KDM4A O75164 6/20 0.97
KDM2A Q9Y2K7 6/20 0.97
INSR P06213 3/20 0.57
CHAT P28329 1/20 0.54
MEN1 O00255 4/20 0.54
MAPT P10636 4/20 0.54
KMT2A Q03164 4/20 0.54
HTT P42858 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
NPSR1 Q6W5P4 2/20 0.54
APAF1 O14727 1/20 0.54
HSP90AA1 P07900 1/20 0.54
MAPK1 P28482 1/20 0.54
BLM P54132 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL313907 1.00 KDM4A (0.97) KDM4AKDM2ACHKAINSRCHRM2
Bromide SCHEMBL10849127 1.00 KDM4A (0.97) KDM4AKDM2ACHKAINSRCHRM2
Bromide SCHEMBL10845282 1.00 KDM4A (0.97) KDM4AKDM2ACHKAINSRCHRM2
Bromide SCHEMBL10845277 1.00 KDM4A (0.97) KDM4AKDM2ACHKAINSRCHRM2
Bromide SCHEMBL10849130 1.00 KDM4A (0.97) KDM4AKDM2ACHKAINSRCHRM2
SCHEMBL10846148 0.98 KDM4A (1.00) KDM4AKDM2ACHKAINSRCHRM2
SCHEMBL13417473 0.98 KDM4A (1.00) KDM4AKDM2ACHKAINSRCHRM2
SCHEMBL21300082 0.98 KDM4A (1.00) KDM4AKDM2ACHKAINSRCHRM2
SCHEMBL10845909 0.98 KDM4A (1.00) KDM4AKDM2ACHKAINSRCHRM2
SCHEMBL10846534 0.98 KDM4A (1.00) KDM4AKDM2ACHKAINSRCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7919755-B2 Dendrimer based electro-optic sensor APPLIED RESEARCH AND PHOTONICS, INC. 2011-04-05 US claimed
US-7854505-B2 Passive and active photonic crystal structures and devices THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2010-12-21 US claimed
US-20090323014-A1 PASSIVE AND ACTIVE PHOTONIC CRYSTAL STRUCTURES AND DEVICES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-31 US claimed
US-20090311799-A1 Nucleic Acid Materials for Nonradiative Energy Transfer and Methods of Production and Use NATIONAL SCIENCE FOUNDATION 2009-12-17 US claimed
WO-2009152492-A1 NUCLEIC ACID MATERIALS FOR NONRADIATIVE ENERGY TRANSFER AND METHODS OF PRODUCTION AND USE UNIVERSITY OF CONNECTICUT (US) 2009-12-17 WO claimed
US-20080128618-A1 Dendrimer Based Electro-Optic Sensor APPLIED RESEARCH AND PHOTONICS, INC. 2008-06-05 US claimed
US-20080099698-A1 Dendrimer Based Terahertz Generator APPLIED RESEARCH AND PHOTONICS, INC. 2008-05-01 US claimed
US-20060182006-A1 Optical record carrier with ase active material, reading device and method for reading such optical record carrier KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2006-08-17 US claimed
EP-1649458-A2 OPTICAL RECORD CARRIER WITH ASE ACTIVE MATERIAL, READING DEVICE AND METHOD FOR READING SUCH OPTICAL RECORD CARRIER Koninklijke Philips Electronics N.V. (NL) 2006-04-26 EP claimed
WO-2005008640-A2 OPTICAL RECORD CARRIER WITH ASE ACTIVE MATERIAL, READING DEVICE AND METHOD FOR READING SUCH OPTICAL RECORD CARRIER KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2005-01-27 WO claimed
US-9093810-B2 Dendrimer based terahertz generator APPLIED RESEARCH AND PHOTONICS, INC. (US) 2015-07-28 US disclosed
US-20120099827-A1 DENDRIMER BASED TERAHERTZ GENERATOR APPLIED RESEARCH AND PHOTONICS, INC. 2012-04-26 US disclosed
US-8093802-B1 Light emitting diode with a deoxyribonucleic acid (DNA) biopolymer THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2012-01-10 US disclosed
US-8050531-B2 Dendrimer based terahertz generator APPLIED RESEARCH AND PHOTONICS, INC. 2011-11-01 US disclosed
US-7919755-B2 Dendrimer based electro-optic sensor APPLIED RESEARCH AND PHOTONICS, INC. 2011-04-05 US disclosed
US-20060182006-A1 Optical record carrier with ase active material, reading device and method for reading such optical record carrier KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2006-08-17 US disclosed
WO-2005056176-A1 ZEOLITES WITH INCORPORATED DIPOLAR NONLINEAR OPTICAL MOLECULES IN UNIFORM ORIENTATION AND PREPARATION THEREOF SOGANG UNIVERSITY CORPORATION (KR) 2005-06-23 WO disclosed
US-5510200-A Films for non-linear optics BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-23 US disclosed
EP-0559701-A1 FILMS FOR NON-LINEAR OPTICS BTG INTERNATIONAL LIMITED (GB) 1993-09-15 EP disclosed
WO-1992009374-A1 FILMS FOR NON-LINEAR OPTICS BRITISH TECHNOLOGY GROUP LTD (GB) 1992-06-11 WO disclosed