Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 11/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391001 | 1.00 | JMJD6 (0.45) | JMJD6MAPK10KMT2ADYRK1AKEAP1 | |
| SCHEMBL18171776 | 0.79 | GABRA1 (0.41) | MAPK10KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL18157906 | 0.74 | KMT2A (0.64) | JMJD6KMT2AKEAP1KDM5BKDM4A | |
| SCHEMBL23119743 | 0.74 | JMJD6 (0.57) | JMJD6KMT2AKEAP1KDM5BKDM4A | |
| SCHEMBL25219200 | 0.74 | JMJD6 (0.45) | JMJD6KMT2AKEAP1KDM5BKDM4A | |
| SCHEMBL30448134 | 0.74 | JMJD6 (0.45) | JMJD6KMT2AKEAP1KDM5BKDM4A | |
| SCHEMBL2684263 | 0.74 | KMO (0.35) | GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL22121738 | 0.74 | ACVR1 (0.41) | JMJD6MAPK10KMT2ADYRK1AKEAP1 | |
| SCHEMBL17339152 | 0.73 | CCNC (0.38) | KMT2AGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL20987177 | 0.73 | DYRK1A (0.53) | DYRK1AGABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067457-A1 | HETEROCYCLIC FUSED RING COMPOUND, AND COMPOSITION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2025-04-03 | — | — | WO | disclosed |