SCHEMBL31391103

SCHEMBL31391103

CC(C)(C)OC(=O)Nc1nc2cc(C(=O)N3CCC4(CCC(=O)NC4=O)C3)ccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 1.00
DDB1 Q16531 2/20 0.49
LCK P06239 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22932129 1.00 CRBN (1.00) CRBNDDB1LCK
SCHEMBL22932498 0.94 CRBN (1.00) CRBNLCK
SCHEMBL22932171 0.88 CRBN (1.00) CRBNDDB1
SCHEMBL22932159 0.81 CRBN (1.00) CRBNDDB1
SCHEMBL22932164 0.81 CRBN (0.79) CRBNDDB1
SCHEMBL21496498 0.81 CRBN (0.85) CRBNDDB1
SCHEMBL21496426 0.74 CRBN (0.85) CRBNDDB1
SCHEMBL21496428 0.73 CRBN (1.00) CRBNDDB1
SCHEMBL21496430 0.72 LCK (0.57) CRBNLCK
SCHEMBL558900 0.72 CRBN (0.65) CRBNLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751456-A Spiro compounds C4医药公司 2025-04-04 CN disclosed
CN-112312904-B Spiro compounds C4医药公司 2025-01-07 CN disclosed