Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 7/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28999502 | 1.00 | PNMT (0.50) | PNMTADRA2AMAPTGRIA1GRIA2 | |
| SCHEMBL21468507 | 0.80 | MAPT (0.49) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8258918 | 0.78 | PNMT (0.55) | PNMTADRA2AMAPTHTR2AHTR2C | |
| SCHEMBL18875031 | 0.77 | PNMT (0.54) | PNMTADRA2AMAPTHTR2AHTR2C | |
| SCHEMBL13875069 | 0.77 | PNMT (0.54) | PNMTADRA2AMAPTTDP1HTR2A | |
| SCHEMBL24869958 | 0.77 | PNMT (0.54) | PNMTADRA2AMAPTHPGDHTR2A | |
| SCHEMBL417912 | 0.77 | MAPT (0.60) | PNMTADRA2AMAPTHTR2AHTR2C | |
| SCHEMBL31335752 | 0.77 | MAPT (0.60) | PNMTADRA2AMAPTHTR2AHTR2C | |
| SCHEMBL24040085 | 0.77 | PNMT (0.54) | PNMTADRA2AMAPTVCAM1HTR2A | |
| SCHEMBL29557821 | 0.77 | MAPT (0.60) | PNMTADRA2AMAPTHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916771-B | Multi-target antitumor compound and preparation method and application thereof | 浙江华海药业股份有限公司 | 2025-04-01 | — | — | CN | disclosed |