Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | PNMT | P11086 | 9/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.54 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557821 | 1.00 | MAPT (0.60) | MAPTALDH1A1PNMTADRA2AASIC3 | |
| SCHEMBL417912 | 1.00 | MAPT (0.60) | MAPTALDH1A1PNMTADRA2AASIC3 | |
| SCHEMBL30997742 | 0.82 | ALDH1A1 (0.61) | MAPTALDH1A1TYMSPKM | |
| SCHEMBL22028064 | 0.82 | ALDH1A1 (0.61) | MAPTALDH1A1TYMSPKM | |
| SCHEMBL8258918 | 0.82 | PNMT (0.55) | MAPTALDH1A1PNMTADRA2AASIC3 | |
| SCHEMBL24040085 | 0.81 | PNMT (0.54) | MAPTALDH1A1PNMTADRA2AASIC3 | |
| SCHEMBL24869958 | 0.81 | PNMT (0.54) | MAPTALDH1A1PNMTADRA2AADRA2B | |
| SCHEMBL13875069 | 0.81 | PNMT (0.54) | MAPTALDH1A1PNMTADRA2AASIC3 | |
| SCHEMBL18875031 | 0.81 | PNMT (0.54) | MAPTALDH1A1PNMTADRA2AASIC3 | |
| SCHEMBL18875034 | 0.81 | PNMT (0.54) | MAPTALDH1A1PNMTADRA2AASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |