Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | MOK | Q9UQ07 | 8/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31392716 | 0.87 | ALDH1A1 (0.64) | KMT2AKDM4EPDE10AALDH1A1MEN1 | |
| SCHEMBL31392697 | 0.86 | MOK (0.59) | KMT2AKDM4EPDE10AALDH1A1MEN1 | |
| SCHEMBL19475440 | 0.85 | KMT2A (0.70) | KMT2AKDM4EPDE10AALDH1A1MEN1 | |
| SCHEMBL26075569 | 0.84 | DHODH (0.48) | KMT2AALDH1A1MEN1PLA2G2ADHODH | |
| SCHEMBL31392768 | 0.84 | PLA2G2A (0.56) | KMT2AKDM4EPDE10AALDH1A1MEN1 | |
| SCHEMBL26075573 | 0.81 | DHODH (0.45) | KMT2AALDH1A1MEN1MAPTHPGD | |
| SCHEMBL31392724 | 0.80 | ALDH1A1 (0.53) | KMT2AKDM4EPDE10AALDH1A1MEN1 | |
| SCHEMBL31392713 | 0.79 | KMT2A (0.49) | KMT2AKDM4EPDE10AALDH1A1MEN1 | |
| SCHEMBL31392760 | 0.78 | MOK (0.60) | KMT2AKDM4EPDE10AALDH1A1MEN1 | |
| SCHEMBL26649544 | 0.78 | PLA2G2A (0.65) | KMT2AKDM4EALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350240-A | 4-Quinoline anilines main protease inhibitor and preparation method and medical application thereof | 河南师范大学 | 2025-01-24 | — | — | CN | disclosed |