Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342164 | 1.00 | MAPT (0.36) | MAPTNPSR1RXFP1PARP1AHR | |
| SCHEMBL31472199 | 0.89 | NOTUM (0.32) | MAPTNPSR1RXFP1 | |
| SCHEMBL153211 | 0.79 | AHR (0.45) | MAPTNPSR1RXFP1PARP1AHR | |
| SCHEMBL8011587 | 0.79 | PARP1 (0.37) | PARP1NR3C1PGRNR3C2CYP2A6 | |
| SCHEMBL17178079 | 0.77 | PARP1 (0.33) | PARP1CYP2A6PTGS1PTGS2 | |
| SCHEMBL4100100 | 0.76 | PARP1 (0.39) | MAPTNPSR1RXFP1PARP1NR3C1 | |
| SCHEMBL30079633 | 0.76 | MAPT (0.36) | MAPTNPSR1RXFP1PARP1NR3C1 | |
| SCHEMBL14758337 | 0.76 | MAPT (0.36) | MAPTNPSR1RXFP1PARP1NR3C1 | |
| SCHEMBL21893243 | 0.76 | ALOX15 (0.40) | MAPTNPSR1RXFP1PARP1NR3C1 | |
| SCHEMBL30748780 | 0.76 | PARP1 (0.42) | MAPTNPSR1RXFP1PARP1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |