Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31394015 | 0.89 | MAPT (0.36) | MAPTNPSR1RXFP1 | |
| SCHEMBL6342164 | 0.89 | MAPT (0.36) | MAPTNPSR1RXFP1 | |
| SCHEMBL20416982 | 0.81 | RAPGEF4 (0.35) | NOTUMNPSR1CTNNB1WNT3A | |
| SCHEMBL30783445 | 0.81 | AHR (0.38) | NOTUMMAPTNPSR1RXFP1 | |
| SCHEMBL11119325 | 0.78 | NOTUM (0.47) | NOTUMMAPTNPSR1RXFP1 | |
| SCHEMBL3889397 | 0.78 | AKT1 (0.40) | NOTUMCTNNB1WNT3A | |
| SCHEMBL13114495 | 0.78 | ALOX15 (0.38) | NOTUMMAPTNPSR1RXFP1 | |
| SCHEMBL10093043 | 0.78 | PARP1 (0.44) | NOTUMCTNNB1WNT3A | |
| SCHEMBL13534195 | 0.78 | NOTUM (0.38) | NOTUM | |
| SCHEMBL30748852 | 0.78 | PARP1 (0.33) | NOTUMMAPTNPSR1RXFP1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026270-A1 | BENZO NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2025-02-06 | — | — | WO | disclosed |