Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | GRK5 | P34947 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PRKX | P51817 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129397 | 1.00 | CHEK1 (0.34) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL9426003 | 0.77 | USP30 (0.39) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL929272 | 0.77 | KMT2A (0.42) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL19715553 | 0.77 | MBOAT4 (0.35) | USP8USP7ERBB2 | |
| SCHEMBL21928126 | 0.76 | NQO1 (0.39) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL23595059 | 0.75 | RECQL (0.44) | USP8KMT2ATSHRUSP7RECQL | |
| SCHEMBL17399657 | 0.74 | NOS3 (0.52) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL2946216 | 0.74 | NQO2 (0.34) | MEN1KMT2AUSP7ERBB2 | |
| SCHEMBL3719102 | 0.74 | KDM4E (0.37) | MAPK14USP8ALDH1A1KMT2ALMNA | |
| SCHEMBL24417209 | 0.74 | USP8 (0.36) | CHEK1ABL1PDGFRBPDGFRAFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546608-A | Novel imidazopyridine and pyrazolopyridine sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-02-28 | — | — | CN | disclosed |