Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16898488 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CA12CA1CA9ABCG2 | |
| SCHEMBL18858985 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CA12CA1CA9ABCG2 | |
| SCHEMBL27189795 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CA12CA1CA9ABCG2 | |
| SCHEMBL13764444 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CA12CA1CA9ABCG2 | |
| SCHEMBL16898408 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CA12CA1CA9ABCG2 | |
| SCHEMBL14845475 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CA12CA1CA9ABCG2 | |
| SCHEMBL16898565 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CA12CA1CA9ABCG2 | |
| SCHEMBL16898333 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CA12CA1CA9ABCG2 | |
| SCHEMBL13497897 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CA12CA1CA9ABCG2 | |
| SCHEMBL31145779 | 0.96 | ALDH1A1 (0.39) | ALDH1A1CA12CA1CA9ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025031923-A1 | IMIDAZO[4,5-D]PYRIDAZINE COMPOUNDS AND CONJUGATES THEREOF, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATIONS | SANOFI (FR) | 2025-02-13 | — | — | WO | disclosed |