SCHEMBL14845475

SCHEMBL14845475

Cc1ccc(S(=O)(=O)OCCOCCOCCOCCN=[N+]=[N-])cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA9 Q16790 2/20 0.41
ABCG2 Q9UNQ0 1/20 0.38
MMP2 P08253 3/20 0.37
MMP9 P14780 3/20 0.37
MMP8 P22894 3/20 0.37
MMP13 P45452 3/20 0.37
STAT3 P40763 1/20 0.36
GAA P10253 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
VDR P11473 1/20 0.34
LMNA P02545 1/20 0.34
HSP90AA1 P07900 1/20 0.34
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.34
XBP1 P17861 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16898488 1.00 ALDH1A1 (0.42) ALDH1A1CA12CA1CA9ABCG2
SCHEMBL18858985 1.00 ALDH1A1 (0.42) ALDH1A1CA12CA1CA9ABCG2
SCHEMBL27189795 1.00 ALDH1A1 (0.42) ALDH1A1CA12CA1CA9ABCG2
SCHEMBL13764444 1.00 ALDH1A1 (0.42) ALDH1A1CA12CA1CA9ABCG2
SCHEMBL16898408 1.00 ALDH1A1 (0.42) ALDH1A1CA12CA1CA9ABCG2
SCHEMBL31395440 1.00 ALDH1A1 (0.42) ALDH1A1CA12CA1CA9ABCG2
SCHEMBL16898565 1.00 ALDH1A1 (0.42) ALDH1A1CA12CA1CA9ABCG2
SCHEMBL16898333 1.00 ALDH1A1 (0.42) ALDH1A1CA12CA1CA9ABCG2
SCHEMBL13497897 1.00 ALDH1A1 (0.42) ALDH1A1CA12CA1CA9ABCG2
SCHEMBL31145779 0.96 ALDH1A1 (0.39) ALDH1A1CA12CA1CA9ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014261-A1 TARGETED PROTEIN MODIFICATION WEATHERWAX BIOTECHNOLOGIES CORP (US) 2026-01-15 US disclosed
US-20250367307-A1 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND/OR PREVENTION TORAY INDUSTRIES, INC. (JP) 2025-12-04 US disclosed
US-20250339541-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-11-06 US disclosed
US-20250281630-A1 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND/OR PREVENTION TORAY INDUSTRIES, INC. (JP) 2025-09-11 US disclosed
US-20250249092-A1 CONJUGATE OF CAPRIN-1 ANTIBODY LINKED TO IMMUNE ACTIVATOR FOR CANCER TREATMENT TORAY INDUSTRIES, INC. (JP) 2025-08-07 US disclosed
US-20250223280-A1 POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-07-10 US disclosed
US-20250213699-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-07-03 US disclosed
US-20250186606-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-06-12 US disclosed
WO-2025120085-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-06-12 WO disclosed
US-12312340-B2 Potent ASGPR-binding compounds for the degradation of immunoglobulins and other proteins AVILAR THERAPEUTICS, INC. (US) 2025-05-27 US disclosed
US-8865122-B2 Methods and compositions for protein labelling GENENTECH, INC. (US) 2014-10-21 US disclosed
WO-2014100367-A1 SYNTHESIS OF FR901464 AND ANALOGS WITH ANTITUMOR ACTIVITY UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2014-06-26 WO disclosed
US-8435488-B2 Methods and compositions for protein labelling GENENTECH, INC. (US) 2013-05-07 US disclosed
US-8415472-B2 Water soluble photochromic compounds for labeling of biomolecules and method for detecting biomolecules using the same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2013-04-09 US disclosed
CN-102333548-B Methods and compositions for protein labelling GENENTECH INC 2013-01-30 CN disclosed
CN-102333548-A Methods and compositions for protein labelling GENENTECH INC 2012-01-25 CN disclosed
CN-101921263-A 2-metridazloe derivative as well as application and preparation method thereof UNIV LANZHOU 2010-12-22 CN disclosed
US-20100256397-A1 WATER SOLUBLE PHOTOCHROMIC COMPOUNDS FOR LABELING OF BIOMOLECULES AND METHOD FOR DETECTING BIOMOLECULES USING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2010-10-07 US disclosed
US-20100256397-A1 WATER SOLUBLE PHOTOCHROMIC COMPOUNDS FOR LABELING OF BIOMOLECULES AND METHOD FOR DETECTING BIOMOLECULES USING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2010-10-07 US disclosed
US-20100221176-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. 2010-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12312340-B2 Potent ASGPR-binding compounds for the degradation of immunoglobulins and other proteins ASGR1, FCGR2A, FCGR3B ALDH1A1 3256/4885CA12 3306/4885CA1 4415/4885
US-20250339541-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS ASGR1, ENGASE, FCGR2A ALDH1A1 3319/4885CA12 2765/4885CA1 4078/4885
US-20250186606-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES BCR, TBCD, TBC1D5 ALDH1A1 2138/4885CA12 1371/4885CA1 3565/4885
US-20100221176-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING RAB5IF, RPS27A, PSMA6 ALDH1A1 4242/4885CA12 1183/4885CA1 910/4885
US-20250213699-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS ASGR1, ENGASE, FCGR2A ALDH1A1 3319/4885CA12 2765/4885CA1 4078/4885
US-20250223280-A1 POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS ASGR1, FCGR2A, FCGR3B ALDH1A1 3256/4885CA12 3306/4885CA1 4415/4885
US-20250367307-A1 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND/OR PREVENTION CAPRIN1, NOS1, NCBP1 ALDH1A1 2547/4885CA12 2469/4885CA1 828/4885
US-20260014261-A1 TARGETED PROTEIN MODIFICATION MDM2, TP53, VHL ALDH1A1 4015/4885CA12 3614/4885CA1 3879/4885
US-20100256397-A1 WATER SOLUBLE PHOTOCHROMIC COMPOUNDS FOR LABELING OF BIOMOLECULES AND METHOD FOR DETECTING BIOMOLECULES USING THE SAME MB, RBP1, TTR ALDH1A1 771/4885CA12 1008/4885CA1 2453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.