Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.56 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31589671 | 0.84 | BRD4 (0.56) | BRD4PARG | |
| SCHEMBL31395489 | 0.83 | BRD4 (0.59) | BRD4 | |
| SCHEMBL31395483 | 0.82 | BRD4 (0.54) | BRD4 | |
| SCHEMBL31395704 | 0.80 | BRD4 (0.52) | BRD4 | |
| SCHEMBL31395392 | 0.80 | BRD4 (0.53) | BRD4 | |
| SCHEMBL31589747 | 0.78 | BRD4 (0.55) | BRD4 | |
| SCHEMBL31590455 | 0.78 | BRD4 (0.58) | BRD4 | |
| SCHEMBL31395367 | 0.76 | BRD4 (0.47) | BRD4 | |
| SCHEMBL31395287 | 0.76 | BRD4 (0.45) | BRD4 | |
| SCHEMBL17492897 | 0.75 | BRD4 (0.52) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739307-A2 | TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY | The General Hospital Corporation (US) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025010291-A2 | TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY | THE GENERAL HOSPITAL CORPORATION (US) | 2025-01-09 | — | — | WO | disclosed |