Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | ALPL | P05186 | 4/20 | 0.57 |
| ▸ | ALPG | P10696 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | JAK2 | O60674 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952091 | 1.00 | MAPT (0.60) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL21951986 | 0.88 | MAPT (0.71) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL21952028 | 0.88 | HPGD (0.57) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL31396326 | 0.88 | HPGD (0.57) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL24209682 | 0.84 | MAPT (0.71) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL21952080 | 0.84 | HPGD (0.58) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL30296021 | 0.83 | CPB1 (0.48) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL24209664 | 0.82 | ALPL (0.73) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL24209657 | 0.82 | MAPT (0.82) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL24209661 | 0.82 | MAPT (0.64) | MAPTHPGDKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768422-B | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2025-03-04 | — | — | CN | disclosed |