Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 9/20 | 0.48 |
| ▸ | CDC7 | O00311 | 9/20 | 0.46 |
| ▸ | CDK2 | P24941 | 4/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792630 | 0.82 | CDC7 (0.47) | JAK2CDC7CDK2ROCK1CDK1 | |
| SCHEMBL3393995 | 0.77 | HSP90AA1 (0.55) | JAK2CDC7CDK2ROCK1CDK1 | |
| SCHEMBL10831613 | 0.72 | PARP1 (0.46) | — | |
| SCHEMBL5000417 | 0.72 | CDC7 (0.51) | JAK2CDC7CDK2ROCK1CDK1 | |
| SCHEMBL3658282 | 0.71 | MKNK1 (0.54) | JAK2CDC7CDK2ROCK1GSK3B | |
| SCHEMBL27932338 | 0.70 | CDC7 (0.47) | JAK2CDC7CDK2ROCK1CDK1 | |
| SCHEMBL28557204 | 0.69 | CYP1A2 (0.42) | JAK2CDK2ROCK1PRKACACDK5 | |
| SCHEMBL3792633 | 0.67 | HSP90AA1 (0.47) | CDK2ROCK1GSK3BPDPK1PIM1 | |
| SCHEMBL22807531 | 0.67 | KDM5C (0.63) | PRKACA | |
| SCHEMBL1004660 | 0.66 | PARP1 (0.50) | PRKACAIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12208098-B2 | 4-carbonylamino-4-phenylpyrimidine compound or pharmaceutically acceptable salt thereof | GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2025-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12208098-B2 | 4-carbonylamino-4-phenylpyrimidine compound or pharmaceutically acceptable salt thereof | SLC5A1, SLC10A1, DPP4 | JAK2 319/4885CDC7 4671/4885CDK2 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.