Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 4/20 | 0.43 |
| ▸ | BECN1 | Q14457 | 4/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16073030 | 0.81 | CYP17A1 (0.46) | CYP17A1PSMB8MAP4K4CD274NAMPT | |
| SCHEMBL23840613 | 0.79 | NAMPT (0.47) | GPR119NAMPT | |
| SCHEMBL20865536 | 0.78 | CYP17A1 (0.68) | CYP17A1PSMB8MAP4K4CD274NAMPT | |
| SCHEMBL11942673 | 0.77 | TRPV1 (0.43) | CYP17A1GPR119PSMB8 | |
| SCHEMBL13055402 | 0.76 | CYP17A1 (0.59) | CYP17A1PSMB8MAP4K4NAMPTMAPK14 | |
| SCHEMBL14087508 | 0.76 | GSK3B (0.40) | CYP17A1GPR119PSMB8MAP4K4NAMPT | |
| SCHEMBL26328838 | 0.75 | CYP17A1 (0.55) | CYP17A1PSMB8MAP4K4CD274NAMPT | |
| SCHEMBL26328883 | 0.75 | CYP17A1 (0.55) | CYP17A1PSMB8MAP4K4CD274NAMPT | |
| SCHEMBL11029675 | 0.75 | P2RY14 (0.42) | CYP17A1PSMB8MAP4K4CD274NAMPT | |
| SCHEMBL6819178 | 0.74 | NAMPT (0.57) | CYP17A1PSMB8CD274NAMPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024262911-A1 | NOVEL PYRAZOLO PYRIMIDINE-BASED COMPOUND AND USE THEREOF | 주식회사 에이조스바이오 | 2024-12-26 | — | — | WO | disclosed |