Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 4/20 | 0.55 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 3/20 | 0.43 |
| ▸ | BECN1 | Q14457 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26328838 | 0.85 | CYP17A1 (0.55) | CYP17A1PSMB8NAMPTMAP4K4CD274 | |
| SCHEMBL20865536 | 0.82 | CYP17A1 (0.68) | CYP17A1PSMB8NAMPTMAP4K4PRKDC | |
| SCHEMBL26330221 | 0.82 | CYP17A1 (0.52) | CYP17A1PSMB8NAMPTMAP4K4PRKDC | |
| SCHEMBL13055402 | 0.80 | CYP17A1 (0.59) | CYP17A1PSMB8NAMPTMAP4K4 | |
| SCHEMBL29582523 | 0.80 | CYP17A1 (0.40) | CYP17A1PSMB8NAMPTMAP4K4HDAC1 | |
| SCHEMBL16616006 | 0.79 | NAMPT (0.53) | CYP17A1NAMPTHDAC1HDAC6MAPT | |
| SCHEMBL29583356 | 0.79 | CYP17A1 (0.59) | CYP17A1MAP4K4PRKDC | |
| SCHEMBL3360413 | 0.77 | CYP17A1 (0.63) | CYP17A1PSMB8NAMPTMAP4K4CD274 | |
| SCHEMBL4759920 | 0.77 | CYP17A1 (0.79) | CYP17A1PSMB8NAMPTMAP4K4CD274 | |
| SCHEMBL18570243 | 0.76 | CYP17A1 (0.61) | CYP17A1PSMB8NAMPTMAP4K4CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
| US-20220106278-A1 | REAGENTS AND METHODS FOR TETRAZINE SYNTHESIS | UNIVERSITY OF DELAWARE (US) | 2022-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | TST, CYP4F8, CYP4Z1 | CYP17A1 404/4885PSMB8 1717/4885NAMPT 1678/4885 |
| US-20220106278-A1 | REAGENTS AND METHODS FOR TETRAZINE SYNTHESIS | TST, CYP4F8, CYP4Z1 | CYP17A1 404/4885PSMB8 1717/4885NAMPT 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.