Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24005756 | 0.83 | CDK8 (0.47) | CDK8KDM4ENPSR1CHEK1ABL1 | |
| SCHEMBL18984392 | 0.82 | GRIN2D (0.41) | CDK8KDM4EALDH1A1ROCK2 | |
| SCHEMBL30452148 | 0.81 | CDK8 (0.46) | CDK8KDM4ENPSR1CHEK1ABL1 | |
| SCHEMBL20551884 | 0.81 | CDK8 (0.46) | CDK8KDM4ENPSR1CHEK1ABL1 | |
| SCHEMBL25650901 | 0.79 | CDK8 (0.44) | CDK8KDM4ENPSR1CHEK1ABL1 | |
| SCHEMBL25613170 | 0.79 | CDK8 (0.44) | CDK8KDM4ENPSR1CHEK1ABL1 | |
| SCHEMBL31497493 | 0.78 | CHEK1 (0.50) | CDK8KDM4ECHEK1ABL1L3MBTL1 | |
| SCHEMBL28139173 | 0.78 | CHEK1 (0.50) | CDK8KDM4ECHEK1ABL1L3MBTL1 | |
| SCHEMBL16506119 | 0.74 | KDM4E (0.41) | CDK8KDM4EPKMRCE1NPSR1 | |
| SCHEMBL4792436 | 0.73 | CDK8 (0.47) | CDK8KDM4ECHEK1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025069270-A1 | AZAINDOLE COMPOUND AND MEDICINE | 日本新薬株式会社 | 2025-04-03 | — | — | WO | disclosed |
| WO-2025070627-A1 | AZAINDOLE COMPOUND AND MEDICAL DRUG | 日本新薬株式会社 | 2025-04-03 | — | — | WO | disclosed |