Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 14/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | NOS3 | P29474 | 11/20 | 0.59 |
| ▸ | NOS2 | P35228 | 6/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387587 | 0.81 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL6226312 | 0.80 | CA12 (0.47) | NOS1CA12CA1CA2CA9 | |
| SCHEMBL8335518 | 0.80 | NOS1 (0.71) | NOS1NOS3NOS2NPC1 | |
| SCHEMBL6225144 | 0.80 | NOS1 (0.71) | NOS1NOS3NOS2NPC1 | |
| SCHEMBL7403875 | 0.78 | NOS1 (0.64) | NOS1NOS3NOS2MEN1KMT2A | |
| SCHEMBL10189842 | 0.78 | NOS1 (0.64) | NOS1NOS3NOS2MEN1KMT2A | |
| 4-Guanidino-Benzoic Acid SCHEMBL1363882 | 0.78 | CA12 (1.00) | NOS1CA12CA1CA2CA9 | |
| Iodide SCHEMBL8621155 | 0.76 | NOS1 (0.66) | NOS1NOS3NOS2MEN1KMT2A | |
| SCHEMBL31415103 | 0.76 | CA1 (0.73) | NOS1CA12CA1CA2CA9 | |
| SCHEMBL8335185 | 0.76 | TPMT (0.50) | NOS1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025039979-A1 | PROTEIN ARGININE METHYLTRANSFERASE-5 INHIBITOR AND PHARMACEUTICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2025-02-27 | — | — | WO | disclosed |