Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18257152 | 1.00 | KDR (0.73) | KDRHTTHDAC6L3MBTL1GAA | |
| SCHEMBL18257156 | 0.85 | KDR (0.74) | KDRHTTHDAC6L3MBTL1GAA | |
| SCHEMBL17552183 | 0.85 | HDAC6 (0.77) | KDRHTTHDAC6L3MBTL1GAA | |
| SCHEMBL29911198 | 0.85 | HDAC6 (0.77) | KDRHTTHDAC6L3MBTL1GAA | |
| SCHEMBL29205661 | 0.84 | KDR (1.00) | KDRHTTHDAC6L3MBTL1GAA | |
| SCHEMBL18257154 | 0.84 | TDP1 (0.74) | KDRHTTHDAC6L3MBTL1GAA | |
| SCHEMBL6645868 | 0.82 | HTT (1.00) | KDRHTTHDAC6L3MBTL1GAA | |
| SCHEMBL29647754 | 0.81 | HDAC6 (1.00) | KDRHTTHDAC6L3MBTL1GAA | |
| SCHEMBL15270551 | 0.81 | HDAC6 (0.79) | KDRHTTHDAC6L3MBTL1GAA | |
| SCHEMBL19631488 | 0.81 | HDAC6 (1.00) | KDRHTTHDAC6L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025039979-A1 | PROTEIN ARGININE METHYLTRANSFERASE-5 INHIBITOR AND PHARMACEUTICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2025-02-27 | — | — | WO | disclosed |